SOD supplement may protect against atherosclerosis
By staff reporter, 3/14/2007
A superoxide dismutase (SOD) supplement, GliSODin, in combination with diet and lifestyle changes can significantly reduce the risk of cardiovascular disease, French researchers have reported.
SOD has a different mode of action to vitamins. First discovered in 1968, it is the first antioxidant mobilized by the cell for defence. It is thought to be more powerful than antioxidant vitamins as it activates the body's productions of its own antioxidants, including catalase and glutathione peroxidase.
Read the full news report from here @ Nutra Ingredients USA
Tuesday, March 27, 2007
Isis cholesterol drug lowers LDL levels
Isis cholesterol drug lowers LDL levels
26th March 2007, By Victoria Harrison
Isis Pharmaceuticals has said new results from its monotherapy phase II clinical trial of cholesterol drug showed improvements in LDL cholesterol.
Patients with high cholesterol were treated for ten weeks with 400 mg/week of the drug ISIS 301012. In this study, increasing the dose of ISIS 301012 to 400 mg/week was well tolerated and further reduced atherogenic lipids, with median improvements in LDL-cholesterol of 70%.
Read the full report here @ Pharmaceutical Business Review Online
26th March 2007, By Victoria Harrison
Isis Pharmaceuticals has said new results from its monotherapy phase II clinical trial of cholesterol drug showed improvements in LDL cholesterol.
Patients with high cholesterol were treated for ten weeks with 400 mg/week of the drug ISIS 301012. In this study, increasing the dose of ISIS 301012 to 400 mg/week was well tolerated and further reduced atherogenic lipids, with median improvements in LDL-cholesterol of 70%.
Read the full report here @ Pharmaceutical Business Review Online
Hemochromatosis gene linked to stroke risk
Hemochromatosis gene linked to stroke risk
Mar 26, 2007
NEW YORK (Reuters Health) - Patients with a specific gene variation for hereditary hemochromatosis, an autosomal recessive disease associated with increased iron accumulation, have more than double the risk of stroke, new research suggests.
Hemochromatosis affects how the body metabolizes iron, which results an iron build-up in the liver. Without treatment, the condition causes liver enlargement that can lead to cirrhosis or liver cancer. The disease can also cause diabetes, heart disease, arthritis, and other serious conditions.
Read the full report here @ Reuters, UK
Mar 26, 2007
NEW YORK (Reuters Health) - Patients with a specific gene variation for hereditary hemochromatosis, an autosomal recessive disease associated with increased iron accumulation, have more than double the risk of stroke, new research suggests.
Hemochromatosis affects how the body metabolizes iron, which results an iron build-up in the liver. Without treatment, the condition causes liver enlargement that can lead to cirrhosis or liver cancer. The disease can also cause diabetes, heart disease, arthritis, and other serious conditions.
Read the full report here @ Reuters, UK
Experimental Heart Drug Fails to Slow Atherosclerosis
Cholesterol News: Experimental Heart Drug Fails to Slow Atherosclerosis
By Marcia Trahan, March 26, 2007
Three new studies found that torcetrapib, an experimental heart drug, did not inhibit atherosclerosis, or plaque build-up in coronary arteries.
Two studies' results were presented March 26 at the American College of Cardiology's annual meeting in New Orleans. A third study will appear in the March 29 issue of the New England Journal of Medicine.
"Something very strange is going on with this drug [torcetrapib], where none of these fantastic changes translate into benefit for the arterial walls," said Dr. John J.P. Kastelein of the Academic Medical Center in Amsterdam, who led the research team for two of the three studies.
Read the full news story from here @ Associated Content
By Marcia Trahan, March 26, 2007
Three new studies found that torcetrapib, an experimental heart drug, did not inhibit atherosclerosis, or plaque build-up in coronary arteries.
Two studies' results were presented March 26 at the American College of Cardiology's annual meeting in New Orleans. A third study will appear in the March 29 issue of the New England Journal of Medicine.
"Something very strange is going on with this drug [torcetrapib], where none of these fantastic changes translate into benefit for the arterial walls," said Dr. John J.P. Kastelein of the Academic Medical Center in Amsterdam, who led the research team for two of the three studies.
Read the full news story from here @ Associated Content
Pfizer says new studies show higher dose of Lipitor slows atherosclerosis
Pfizer says new studies show higher dose of Lipitor slows atherosclerosis
26 Mar 2007
LONDON (AFX) - Pfizer Inc said results from two new imaging trials show a higher dose of its cholesterol-fighting drug Lipitor stopped the progression of atherosclerosis in patients with coronary heart disease or familial hypercholesterolemia (FH).
The results are part of three, two-year clinical trials, involving over 2,800 patients, designed to investigate the efficacy of torcetrapib in combination with Lipitor compared to Lipitor alone.
Read the full report from here @ Forbes
26 Mar 2007
LONDON (AFX) - Pfizer Inc said results from two new imaging trials show a higher dose of its cholesterol-fighting drug Lipitor stopped the progression of atherosclerosis in patients with coronary heart disease or familial hypercholesterolemia (FH).
The results are part of three, two-year clinical trials, involving over 2,800 patients, designed to investigate the efficacy of torcetrapib in combination with Lipitor compared to Lipitor alone.
Read the full report from here @ Forbes
ACC: Atherosclerosis Impervious to HDL Infusions
ACC: Atherosclerosis Impervious to HDL Infusions
By Crystal Phend, Staff Writer, MedPage Today
March 26, 2007
NEW ORLEANS, March 26 -- Artificially boosting high-density lipoprotein (HDL) levels does not reverse atherosclerosis, though it may have some vascular benefit, said researchers here.
In the ERASE trial of 183 patients with recent acute coronary syndromes, weekly infusions of CSL-111, an investigational agent made with reconstituted HDL from human plasma, showed no significant advantage over placebo in reducing plaque volumes...
However, there were significant improvements in atheroma volume versus baseline with the agent as well as in plaque characteristics and coronary scores versus placebo "strongly suggestive of rapid beneficial effects" ...
Read the full news report here @ The Med Page
By Crystal Phend, Staff Writer, MedPage Today
March 26, 2007
NEW ORLEANS, March 26 -- Artificially boosting high-density lipoprotein (HDL) levels does not reverse atherosclerosis, though it may have some vascular benefit, said researchers here.
In the ERASE trial of 183 patients with recent acute coronary syndromes, weekly infusions of CSL-111, an investigational agent made with reconstituted HDL from human plasma, showed no significant advantage over placebo in reducing plaque volumes...
However, there were significant improvements in atheroma volume versus baseline with the agent as well as in plaque characteristics and coronary scores versus placebo "strongly suggestive of rapid beneficial effects" ...
Read the full news report here @ The Med Page
Crestor Effective at Halting Early Atherosclerosis
Crestor Effective at Halting Early Atherosclerosis
This press release issued by Eurekalert says that an international study using ultrasound technology has found that the most potent cholesterol-lowering drug is also effective at halting early changes in the blood vessels that can lead to atherosclerosis.
Results from the study were reported at the annual meeting of the American College of Cardiology in New Orleans and were published on-line by the Journal of the American Medical Association. The research involved people with moderately elevated cholesterol levels who didn't qualify for treatment under national guidelines.
Read the full news report from the Hindu
This press release issued by Eurekalert says that an international study using ultrasound technology has found that the most potent cholesterol-lowering drug is also effective at halting early changes in the blood vessels that can lead to atherosclerosis.
Results from the study were reported at the annual meeting of the American College of Cardiology in New Orleans and were published on-line by the Journal of the American Medical Association. The research involved people with moderately elevated cholesterol levels who didn't qualify for treatment under national guidelines.
Read the full news report from the Hindu
Detecting Artery Disease In Your Legs - PAD
Detecting Artery Disease In Your Legs - PAD
March 23, 2007
New research finds it's in your legs not your chest that some of the most subtle signs of cardiovascular disease can appear.
The condition is called peripheral arterial disease, or PAD.
PAD affects about 10 million people in the United States. In its early stages, there may be no symptoms. Doctors say to be alert to any pain in the legs while walking that goes away when you rest. Other symptoms include swelling or numbness in the leg, sores that won't heal, or a change in the color of your leg.
Those at highest risk for PAD include anyone over age 50, people with a family history of cardiovascular disease, and anyone with diabetes, high blood pressure, or high cholesterol.
Read the full report from here @ Click on Detroit
March 23, 2007
New research finds it's in your legs not your chest that some of the most subtle signs of cardiovascular disease can appear.
The condition is called peripheral arterial disease, or PAD.
PAD affects about 10 million people in the United States. In its early stages, there may be no symptoms. Doctors say to be alert to any pain in the legs while walking that goes away when you rest. Other symptoms include swelling or numbness in the leg, sores that won't heal, or a change in the color of your leg.
Those at highest risk for PAD include anyone over age 50, people with a family history of cardiovascular disease, and anyone with diabetes, high blood pressure, or high cholesterol.
Read the full report from here @ Click on Detroit
Peripheral Vascular Disease: Keeping the Blood Flowing
Peripheral Vascular Disease: Keeping the Blood Flowing
09 March 2007, By Steve Tokar
Peripheral arterial disease (PAD) can result in “big trouble, and eventually lead to gangrene and amputation.” But not for all patients: Some grow new arteries when the old artery is blocked. Others do not, though, “and those are the ones who get into trouble.”
The problem, according to a surgeon, is that no one knows a reason for the difference. “We’ve come up with a lot of treatments for cleaning up, scraping out and bypassing arteries without really understanding why some patients have a poor response to PAD.”
Read the full report here @ UCSF
09 March 2007, By Steve Tokar
Peripheral arterial disease (PAD) can result in “big trouble, and eventually lead to gangrene and amputation.” But not for all patients: Some grow new arteries when the old artery is blocked. Others do not, though, “and those are the ones who get into trouble.”
The problem, according to a surgeon, is that no one knows a reason for the difference. “We’ve come up with a lot of treatments for cleaning up, scraping out and bypassing arteries without really understanding why some patients have a poor response to PAD.”
Read the full report here @ UCSF
Stents Prevent Peripheral Arterial Disease-Related Amputation
Stents Prevent Peripheral Arterial Disease-Related Amputation
By Crystal Phend, Staff Writer, MedPage Today
March 07, 2007
SEATTLE, March 7 -- Angioplasty and stenting of small vessels below the knee are successfully staving off amputation among older patients with severe peripheral arterial disease (PAD), researchers said here.
In a survey among 57 patients at the critical limb ischemia stage of PAD, 92% avoided amputation through two years of follow-up with the treatment, said Nael Saad, M.B., B.Ch., of the University of Rochester (N.Y.) Medical Center.
Read the full report here @ Med Page Today
By Crystal Phend, Staff Writer, MedPage Today
March 07, 2007
SEATTLE, March 7 -- Angioplasty and stenting of small vessels below the knee are successfully staving off amputation among older patients with severe peripheral arterial disease (PAD), researchers said here.
In a survey among 57 patients at the critical limb ischemia stage of PAD, 92% avoided amputation through two years of follow-up with the treatment, said Nael Saad, M.B., B.Ch., of the University of Rochester (N.Y.) Medical Center.
Read the full report here @ Med Page Today
Atherothrombosis Associated With High Rates Of Cardiovascular Events
Atherothrombosis Associated With High Rates Of Cardiovascular Events Within 1 Year
26 Mar 2007
Patients with arterial disease have relatively high rates of experiencing a cardiovascular event (such as heart attack, stroke or cardiovascular death) within one year, and these increase with the number of arterial locations afflicted, according to a large, international study in JAMA.
Read the full news story from here @ Medical News Today
26 Mar 2007
Patients with arterial disease have relatively high rates of experiencing a cardiovascular event (such as heart attack, stroke or cardiovascular death) within one year, and these increase with the number of arterial locations afflicted, according to a large, international study in JAMA.
Read the full news story from here @ Medical News Today
Don't ignore dangerous leg pains - could be PAD!
Don't ignore dangerous leg pains - could be PAD!
Mar 12 2007
By Jane Picken, The Evening Chronicle
Searing pains in the legs are not just unpleasant, they could be the warning signs of blocked arteries and the precursor to a heart attack or stroke. Health reporter Jane Picken finds out about Peripheral Arterial Disease. Read the full news story here @ IC Newcastle
Mar 12 2007
By Jane Picken, The Evening Chronicle
Searing pains in the legs are not just unpleasant, they could be the warning signs of blocked arteries and the precursor to a heart attack or stroke. Health reporter Jane Picken finds out about Peripheral Arterial Disease. Read the full news story here @ IC Newcastle
To fight clotting and DVT, flex leg muscles
To fight clotting & DVT, flex leg muscles
Dr. Richard T. Bosshardt, March 25, 2007
In this interesting article, Dr Bosshardt says that "...studies show that simply putting patients on operating tables -- under anesthesia, irrespective of the surgery -- can increase the risk of DVT...
One of the most effective preventive measures to avoid DVT is early ambulation -- or movement. Unless prohibited by a doctor, patients should make every effort to get out of bed as quickly as possible and begin walking...Even when confined to bed, unless specifically prohibited by their doctor, patients can move and flex their legs, and contract the legs muscles forcefully. This should be done as often as possible...."
Interesting! Read the full article here @ The Orlando Sentinel
Dr. Richard T. Bosshardt, March 25, 2007
In this interesting article, Dr Bosshardt says that "...studies show that simply putting patients on operating tables -- under anesthesia, irrespective of the surgery -- can increase the risk of DVT...
One of the most effective preventive measures to avoid DVT is early ambulation -- or movement. Unless prohibited by a doctor, patients should make every effort to get out of bed as quickly as possible and begin walking...Even when confined to bed, unless specifically prohibited by their doctor, patients can move and flex their legs, and contract the legs muscles forcefully. This should be done as often as possible...."
Interesting! Read the full article here @ The Orlando Sentinel
Don't pin back pain on age - But if you're pushing 50, listen up
Don't pin back pain on age - But if you're pushing 50, listen up
March 23, 2007 - By JANE GLENN HAAS / The Orange County Register
Age can give you an achy back, but don't blame the years; Blame your genes, or your lifestyle. Your parents, your weight, your exercise regime and even your office job contribute to a bad back.
A watershed year for backs is 50...When back pain is accompanied by leg pain, then it's either a herniated disc pinching a nerve (usually for 25- to 45-year-olds) or it's from spinal stenosis (for those 50 and older).
Read more from this news report @ Dallas Morning News
March 23, 2007 - By JANE GLENN HAAS / The Orange County Register
Age can give you an achy back, but don't blame the years; Blame your genes, or your lifestyle. Your parents, your weight, your exercise regime and even your office job contribute to a bad back.
A watershed year for backs is 50...When back pain is accompanied by leg pain, then it's either a herniated disc pinching a nerve (usually for 25- to 45-year-olds) or it's from spinal stenosis (for those 50 and older).
Read more from this news report @ Dallas Morning News
Wellness: Leg Pain May Be More Than a Pain in the Neck
Wellness: Leg Pain May Be More Than a Pain in the Neck
By Richard J. Bocklett
For people 65 and older, leg pain can be a warning sign for peripheral artery disease (PAD) in which clogged arteries in the body's lower extremities cause decreased blood flow in the legs, resulting in difficulty and pain when walking. PAD can strike anyone regardless of age, but it is most common in men and women over 50, affecting 12 to 20 percent of our older population - as many as 8 to 12 million Americans!
PAD is a common arterial condition, but it can become serious if unattended. It develops most commonly as a result of atherosclerosis, or hardening of the arteries, which occurs when cholesterol and scar tissue build up, forming plaque that narrows and clogs the blood vessels. If untreated, this condition eventually can lead to gangrene and amputation.
This is an excellent article that provides detailed notes about PAD. Read the full news article from the Queen's Ledger here
By Richard J. Bocklett
For people 65 and older, leg pain can be a warning sign for peripheral artery disease (PAD) in which clogged arteries in the body's lower extremities cause decreased blood flow in the legs, resulting in difficulty and pain when walking. PAD can strike anyone regardless of age, but it is most common in men and women over 50, affecting 12 to 20 percent of our older population - as many as 8 to 12 million Americans!
PAD is a common arterial condition, but it can become serious if unattended. It develops most commonly as a result of atherosclerosis, or hardening of the arteries, which occurs when cholesterol and scar tissue build up, forming plaque that narrows and clogs the blood vessels. If untreated, this condition eventually can lead to gangrene and amputation.
This is an excellent article that provides detailed notes about PAD. Read the full news article from the Queen's Ledger here
Minimally invasive procedure eases back pain
Minimally invasive procedure eases back pain
Ask the Doctor: Shari Rudavsky @ Indy Star
Anthony Sabatino, an interventional pain anesthesiologist with Interventional Pain Care Associates in Carmel, Noblesville and Plainfield, discusses treatment for back pain.
See the questions asked about back pain and the answers provided by the doctor
Ask the Doctor: Shari Rudavsky @ Indy Star
Anthony Sabatino, an interventional pain anesthesiologist with Interventional Pain Care Associates in Carmel, Noblesville and Plainfield, discusses treatment for back pain.
See the questions asked about back pain and the answers provided by the doctor
New treatment options for low back pain
New treatment options for low back pain
Monday, March 26, 2007
DR. SHAY S. PATHARE
Low back pain (LBP) is a leading cause of disability in the United States. Low back pain affects up to 70 to 85 percent of people at some point in their lives and is the second most common cause for visiting a physician.
Numerous treatment options exist for LBP including physical therapy, chiropractic, acupuncture, bed rest and various medications. There exists an entire subspecialty of medicine that specializes in a different form of treatment for low back pain. This is the field of interventional pain management, says this report
Read the full news report @ Staten Island Advance
Monday, March 26, 2007
DR. SHAY S. PATHARE
Low back pain (LBP) is a leading cause of disability in the United States. Low back pain affects up to 70 to 85 percent of people at some point in their lives and is the second most common cause for visiting a physician.
Numerous treatment options exist for LBP including physical therapy, chiropractic, acupuncture, bed rest and various medications. There exists an entire subspecialty of medicine that specializes in a different form of treatment for low back pain. This is the field of interventional pain management, says this report
Read the full news report @ Staten Island Advance
Tuesday, March 6, 2007
Mega Millions jackpot swells to record $370 million
Mega Millions jackpot swells to record $370 million
March 6, 2007 , CNN
The multistate Mega Millions game has drawn bettors with a jackpot estimated at a record $370 million.
Because of the huge prize and publicity, the 12 participating states agreed to move Tuesday night's drawing from the game's usual home in Atlanta to New York's Times Square.
Two winners split a $363 million jackpot in 2000.
The competing Powerball game has the record for the largest single winner with $314.9 million, on Christmas Day.
The odds of winning the Mega Millions jackpot are about 1 in 176 million.
Read more from this CNN/AP report
March 6, 2007 , CNN
The multistate Mega Millions game has drawn bettors with a jackpot estimated at a record $370 million.
Because of the huge prize and publicity, the 12 participating states agreed to move Tuesday night's drawing from the game's usual home in Atlanta to New York's Times Square.
Two winners split a $363 million jackpot in 2000.
The competing Powerball game has the record for the largest single winner with $314.9 million, on Christmas Day.
The odds of winning the Mega Millions jackpot are about 1 in 176 million.
Read more from this CNN/AP report
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